How Long Does TMS Take to Work, and How Long Does It Last?

Dr. JeanAnne Johnson, PsyD, PhD, APRN-BC, FNP, PMHNP, PMHS
Mental Health Nurse

Dr. JeanAnne Johnson is a Psychiatric/Mental Health Nurse Practitioner with over 30 years of medical experience. She holds advanced degrees from Georgetown University and Rush University, along with multiple certifications in psychiatric care, addiction treatment, and pediatric mental health. She is currently pursuing a fellowship in Precision Psychiatry and Functional Medicine.

JeanAnne provides psychiatric services across 14 clinics, specializing in mental illnesses, substance use disorders, and criminogenic programs. A national speaker and author of I Can Do Hard Things: Tools to Manage Anxiety When Medication Isn’t Enough (2019), she is passionate about holistic mental health care. Her approach addresses the root causes of mental illness through nutrition, lifestyle changes, and functional medicine.

Outside of work, JeanAnne enjoys outdoor activities with her two children, is a cancer survivor, and loves animals.


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Perhaps you’ve heard of Transcranial Magnetic Stimulation (TMS)? If not, it’s a relatively new treatment primarily for treatment-resistant depression and anxiety. And it’s very effective for many people. Read on to learn more about how it works, how long it lasts and its effectiveness.

What is TMS?

TMS is a safe, effective and non-invasive brain stimulation treatment for depression and anxiety. Its effectiveness How Long for TMS to Work and Does it Last? 

Transcranial Magnetic Stimulation (TMS) is a promising treatment for people struggling with treatment-resistant depression and anxiety. How does it work, and how long do its effects last? Read on to find out more about this revolutionary treatment. 

What is TMS?

TMS is a non-invasive, safe, and effective treatment for people with depression and anxiety. It works by using magnetic fields to stimulate specific areas of the brain involved in mood regulation, helping to alleviate symptoms. While TMS is highly effective for many, its impact and duration can vary from person to person. Approved by the FDA in 2008, it has been successfully used for years to help individuals who haven’t found relief from other treatments. 

TMS devices are placed on the scalp, near the front of the brain. Through powerful magnetic pulses, the device stimulates brain activity in the dorsolateral prefrontal cortex, an area linked to depression.  The treatment is non-invasive, meaning no surgery or anesthesia is required. 

TMS is primarily used for individuals with Major Depressive Disorder (MDD)  whose symptoms have not satisfactorily improved with antidepressant medications and therapy [1]. It can also benefit those who struggle with side effects from medications, such as weight gain or sexual dysfunction. TMS can be used on its own or in combination with other treatments. 

While TMS is generally well-tolerated, the most common side effect is a mild headache. It may not be suitable for people at risk of seizures, head injury, or other serious neurological conditions. 

A full course of treatment typically involves daily sessions, five times a week, for 4-6 weeks. Each session lasts between 20-50 minutes depending on the specific treatment plan.[2].

How Long Does TMS Take to Work?

Some individuals may notice slight improvements within 1-2 weeks of starting TMS treatment. For others, more significant changes may not occur until 4-6 weeks into treatment.

How Long Do TMS Results Last?

Most patients experience relief from depressive symptoms shortly after completing treatment. The effects of TMS are generally long-lasting, with 50% of patients sustaining positive outcomes for up to a year. Approximately one-third of these patients experience complete remission. As with all antidepressant treatments, a maintenance plan involving either medication or psychotherapy is recommended to sustain the positive effects of TMS.

Does TMS Work for Other Mental Health Conditions?

Ongoing research and clinical trials are evaluating the effectiveness of TMS for other conditions, including pediatric depression, bipolar disorder, obsessive-compulsive disorder (OCD), smoking cessation, and post-traumatic stress disorder (PTSD). While these uses are still being tested, they are considered “off-label,” meaning they have not yet been FDA-approved for these conditions [2].

The Harper Clinic Approach to TMS

Before starting TMS, a licensed mental health professional must assess whether it’s the right treatment for you. Harper Clinic offers a  3-step consultation process for patients considering TMS.

  1. Get in touch with Harper Clinic via text, phone, website contact, or through their direct Vagaro booking. 
  2. Schedule your first consultation with a provider who will help design a treatment plan tailored to your health needs. 
  3. Your assessment will include insurance verification, a medical history review, and an exploration of your treatment goals and past attempts. Your provider may recommend other treatments, such as medication or conventional therapies (CBT, DBT, or EMDR), depending on your specific case. If TMS is deemed appropriate, the provider will approve you for treatment and schedule your sessions.

Sources

[1] UNC School of Medicine Psychiatry. TMS FAQ.

[2] Stern, A. 2021. Transcranial magnetic stimulation (TMS): Hope for stubborn depression. Harvard Health Publishing.

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